What is so mind blowing about this ‘new’ term is in looking at the research around it, it is well known to happen to those who have had previous vaccines for a viral condition.
-it’s not new because they first noticed this syndrome in the 1960’s cases of RSV treated with a vaccine: Respiratory syncytial virus (RSV) is a common, and very contagious, virus that infects the respiratory tract of most children before their second birthday. For most babies and young children, the infection causes nothing more than a cold – this is until they tried to vaccinate against it.
Antibody-dependent enhancement (ADE), sometimes less precisely called immune enhancement or disease enhancement, is a phenomenon in which binding of a virus to suboptimal antibodies enhances its entry into host cells, followed by its replication.
In general, virus-specific antibodies are considered antiviral and play an important role in the control of virus infections in a number of ways. However, in some instances, the presence of specific antibodies can be beneficial to the virus. This activity is known as antibody-dependent enhancement (ADE) of virus infection. The ADE of virus infection is a phenomenon in which virus-specific antibodies enhance the entry of virus, and in some cases the replication of virus, into monocytes/macrophages and granulocytic cells through interaction with Fc and/or complement receptors. This phenomenon has been reported in vitro and in vivo for viruses representing numerous families and genera of public health and veterinary importance. These viruses share some common features such as preferential replication in macrophages, ability to establish persistence, and antigenic diversity. For some viruses, ADE of infection has become a great concern to disease control by vaccination. Consequently, numerous approaches have been made to the development of vaccines with minimum or no risk for ADE. Identification of viral epitopes associated with ADE or neutralization is important for this purpose. In addition, clear understanding of the cellular events after virus entry through ADE has become crucial for developing efficient intervention. However, the mechanisms of ADE still remain to be better understood.
Antibody-dependent enhancement (ADE) of infection represents a paradoxical phenomenon in host–pathogen biology, in which, antibody, an important pillar of the host defense against invading pathogen, actually allows entry of the pathogen into host territory. This traitorous behavior of the antibody further serves to weaken the host defense system and thus generates an environment conducive for enhanced growth of the pathogen and consequently exacerbates disease in the host. This phenomenon has far-reaching implications for disease control and prevention, as therapeutic antibodies deployed to protect the host may aid the pathogen instead. Similarly, antibodies induced by vaccination may actually increase the risk and/or severity of disease in subsequent host–pathogen encounters.
In some, if not all instances with CV, it is the cause of the cytokine storms that overwhelm the body.
In critically sick patients IgG antibodies can be found in higher levels at certain disease stage. A positive relationship between high IgG antibody titers and COVID-19 severity supports the hypothesis that connects the disease pathogenesis and antibodies production in a causative way. It is not clear, however, if this connection is a result of enhanced immune-cell infection, or direct production of pathogenic and auto-reactive antibodies. Further, It is now understood that mature B cells may have pathological effects independently of antibody production through the direct secretion of cytokines. Antibodies also can harm without promoting infection of immune cells if they are auto-antibodies against type I IFNs. Thus, it has been found that 10% of patients with life-threatening COVID-19 have such antibodies, while some of these antibodies target IFN-α, some IFN-ω, or both.
The pathogenesis of SARS, MERS and COVID-19 diseases, may be associated with ADE, manifested in the infection of monocytes, macrophages and B-cells during primary infection. Some researchers believe that ADE is a key step in COVID-19 evolution from the mild to severe form with critical symptoms.
ADE along with type 2 T helper cell-dependent mechanisms may contribute to a development of the vaccine associated disease enhancement (VADE), which is not limited to respiratory disease. VADE might hamper vaccine development, as a vaccine may trigger the production of antibodies which, via ADE I This is a decisive issue during late clinical stages of vaccine development against COVID-19. Some vaccine candidates that targeted coronaviruses, RSV virus and Dengue virus elicited VADE, and were terminated from further development or became approved for use only for patients who have had those viruses before.
Ok, from just this small amount reading, all conjecture aside, WTF?!?! You’d think by now that I could have at least accepted the lunacy, the ludicrousness of the whole last year. All the research I’ve done, the journal papers, the white papers, hours listening to researchers and informed fearless doctors, THAT I WOULD BE OVER IT. But it seems I’m not, maybe because I just can’t understand wanting to kill so many, with so little care about it.
You know, if they knew back in the 60’s that when dealing with viruses, immunizations were most likely to help accelerate the illness instead of prevent it, then THE CURRENT CV19 VACCINATIONS ONLY PURPOSE IS TO MAKE AN INFECTION MORE DEADLY!!! THEY COMMIT MURDER AND ITS JUST A QUESTION OF THE TYPE OF WEAPON!!!
If you have ever had a flu shot in your entire life time, you are at high risk from what ever version, or mutation of the CV19 – original or otherwise and you should be afraid, very afraid.
If I ever wanted rock solid reasons why I will NEVER-EVER get a vaccination, there they are.
But really – now they want the whole world to be vaccinated? They are using terms like vaccine hesitancy, and gaslighting the public with rhetoric and fear. Go look at the Gates funded world institutions like the WHO and HHS and look for their policy on Agenda 2020.
Maybe they don’t value or even know about the sanctity of life because really, they are all dead …
(yeah I’m pissed off, mortified and spittin’ angry, incredulous and sick at heart – and guess what? I’M DAMNED TIRED OF IT.)